CircTLK1 modulates sepsis‐induced cardiomyocyte apoptosis via enhancing PARP1/HMGB1 axis–mediated mitochondrial DNA damage by sponging miR‐17‐5p

INTRODUCTION: Septic cardiomyopathy is a common complication of sepsis with high morbidity and mortality, but lacks specific therapy. This study aimed to reveal the role of circTLK1 and its potential mechanisms in septic cardiomyopathy. MATERIALS AND METHODS: The in vitro and in vivo models of septi...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Yu, Yu, Ying, Qin, Xiao‐Mei, Jiang, Tao, Tan, Yan‐Fang, Ouyang, Wen‐Xian, Xiao, Zheng‐Hui, Li, Shuang‐Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419196/
https://www.ncbi.nlm.nih.gov/pubmed/34410682
http://dx.doi.org/10.1111/jcmm.16738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419196/
https://www.ncbi.nlm.nih.gov/pubmed/34410682
http://dx.doi.org/10.1111/jcmm.16738

Ejemplares similares