MicroRNA-221-3p Suppresses the Microglia Activation and Seizures by Inhibiting of HIF-1α in Valproic Acid-Resistant Epilepsy

One-third of patients with epilepsy suffer from drug-resistant epilepsy (DRE). Valproic acid (VPA) is a classic anticonvulsant drug, and its resistance is a crucial predictor of DRE, but the pathogenesis remain unknown. Most patients with VPA-resistant epilepsy appear distinct inflammatory response...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Meng, Zhu, Yiqing, Zhang, Junqi, Wu, Wei, Sun, Yunxia, Zhang, Xuemei, Tao, Jie, Li, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419275/
https://www.ncbi.nlm.nih.gov/pubmed/34497517
http://dx.doi.org/10.3389/fphar.2021.714556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419275/
https://www.ncbi.nlm.nih.gov/pubmed/34497517
http://dx.doi.org/10.3389/fphar.2021.714556

Ejemplares similares