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Does chronic dietary exposure to the mycotoxin deoxynivalenol affect the porcine hepatic transcriptome when an acute-phase response is initiated through first or second-pass LPS challenge of the liver?

The sensitivity of pigs to deoxynivalenol (DON) might be increased by systemic inflammation (SI), which also has consequences for hepatic integrity. Liver lesions and a dys-regulated gene network might hamper hepatic handling and elimination of DON whereby the way of initiation of hepatic inflammati...

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Detalles Bibliográficos
Autores principales: Dänicke, Sven, Heymann, Ann-Katrin, Oster, Michael, Wimmers, Klaus, Tesch, Tanja, Bannert, Erik, Bühler, Susanne, Kersten, Susanne, Frahm, Jana, Kluess, Jeannette, Kahlert, Stefan, Rothkötter, Hermann-Josef, Billenkamp, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419296/
https://www.ncbi.nlm.nih.gov/pubmed/34338001
http://dx.doi.org/10.1177/17534259211030563