Intracellular Accumulation of IFN-λ4 Induces ER Stress and Results in Anti-Cirrhotic but Pro-HCV Effects

IFNL3/IFNL4 polymorphisms are inversely associated with the risk of chronic hepatitis C virus (HCV) infection and cirrhosis, two major risk factors for developing hepatocellular carcinoma (HCC). To further explore these inverse associations and their molecular underpinnings, we analyzed IFNL3/IFNL4...

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Detalles Bibliográficos
Autores principales: Onabajo, Olusegun O., Wang, Fang, Lee, Mei-Hsuan, Florez-Vargas, Oscar, Obajemu, Adeola, Tanikawa, Chizu, Vargas, Joselin M., Liao, Shu-Fen, Song, Ci, Huang, Yu-Han, Shen, Chen-Yang, Banday, A. Rouf, O’Brien, Thomas R., Hu, Zhibin, Matsuda, Koichi, Prokunina-Olsson, Ludmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419317/
https://www.ncbi.nlm.nih.gov/pubmed/34497603
http://dx.doi.org/10.3389/fimmu.2021.692263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419317/
https://www.ncbi.nlm.nih.gov/pubmed/34497603
http://dx.doi.org/10.3389/fimmu.2021.692263

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