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miR-377-3p-Mediated EGR1 Downregulation Promotes B[a]P-Induced Lung Tumorigenesis by Wnt/Beta-Catenin Transduction

Polycyclic aromatic hydrocarbons (PAHs), particularly benzo[a]pyrene (B[a]P), found in cigarette smoke and air pollution, is an important carcinogen. Nevertheless, early molecular events and related regulatory effects of B[a]P-mediated cell transformation and tumor initiation remain unclear. This st...

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Detalles Bibliográficos
Autores principales: Ke, Xinxin, He, Lulu, Wang, Runan, Shen, Jing, Wang, Zhengyang, Shen, Yifei, Fan, Longjiang, Shao, Jimin, Qi, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419355/
https://www.ncbi.nlm.nih.gov/pubmed/34497759
http://dx.doi.org/10.3389/fonc.2021.699004