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Swertianolin ameliorates immune dysfunction in sepsis via blocking the immunosuppressive function of myeloid-derived suppressor cells

In this study, we studied the long-term proliferation trajectory of myeloid-derived suppressor cells (MDSCs) in murine sepsis model and investigated whether swertianolin could modulate the immunosuppressive function of MDSCs. A murine sepsis model was established by cecal ligation and perforation (C...

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Detalles Bibliográficos
Autores principales: Ren, Zongfang, Tang, Haoran, Wan, Linjun, Liu, Xing, Tang, Ning, Wang, Lingling, Guo, Zhenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419598/
https://www.ncbi.nlm.nih.gov/pubmed/34468107
http://dx.doi.org/10.4081/ejh.2021.3292