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CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65

The E3 ubiquitin ligase complex CDC20‐activated anaphase‐promoting complex/Cyclosome (APC/C(CDC20)) plays a critical role in governing mitotic progression by targeting key cell cycle regulators for degradation. Cell division cycle protein 20 homolog (CDC20), the co‐activator of APC/C, is required fo...

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Detalles Bibliográficos
Autores principales: Du, Yangge, Zhang, Min, Liu, Xuejiao, Li, Zheng, Hu, Menglong, Tian, Yueming, Lv, Longwei, Zhang, Xiao, Liu, Yunsong, Zhang, Ping, Zhou, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419691/
https://www.ncbi.nlm.nih.gov/pubmed/34382737
http://dx.doi.org/10.15252/embr.202152576