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Mfn2 localization in the ER is necessary for its bioenergetic function and neuritic development

Mfn2 is a mitochondrial fusion protein with bioenergetic functions implicated in the pathophysiology of neuronal and metabolic disorders. Understanding the bioenergetic mechanism of Mfn2 may aid in designing therapeutic approaches for these disorders. Here we show using endoplasmic reticulum (ER) or...

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Detalles Bibliográficos
Autores principales: Casellas‐Díaz, Sergi, Larramona‐Arcas, Raquel, Riqué‐Pujol, Guillem, Tena‐Morraja, Paula, Müller‐Sánchez, Claudia, Segarra‐Mondejar, Marc, Gavaldà‐Navarro, Aleix, Villarroya, Francesc, Reina, Manuel, Martínez‐Estrada, Ofelia M, Soriano, Francesc X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419703/
https://www.ncbi.nlm.nih.gov/pubmed/34296790
http://dx.doi.org/10.15252/embr.202051954