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Early detection of metastatic uveal melanoma by the analysis of tumor‐specific mutations in cell‐free plasma DNA

BACKGROUND: Eye salvaging therapy of malignant melanomas of the uvea can preserve the eye in most cases, but still about half of patients die from metastatic disease. Previous analyses of cell‐free DNA from plasma had shown detectable levels of tumor‐specific GNAQ/GNA11 mutations in patients with th...

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Detalles Bibliográficos
Autores principales: Le Guin, Claudia H. D., Bornfeld, Norbert, Bechrakis, Nikolaos E., Jabbarli, Leyla, Richly, Heike, Lohmann, Dietmar R., Zeschnigk, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419753/
https://www.ncbi.nlm.nih.gov/pubmed/34291585
http://dx.doi.org/10.1002/cam4.4153