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Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras

Monomeric autotransporters have been used extensively to transport recombinant proteins or protein domains to the cell surface of Gram-negative bacteria amongst others for antigen display. Genetic fusion of such antigens into autotransporters has yielded chimeras that can be used for vaccination pur...

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Detalles Bibliográficos
Autores principales: Phan, Trang H., Kuijl, Coen, Huynh, Dung T., Jong, Wouter S. P., Luirink, Joen, van Ulsen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419823/
https://www.ncbi.nlm.nih.gov/pubmed/34488755
http://dx.doi.org/10.1186/s12934-021-01668-2