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Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras
Monomeric autotransporters have been used extensively to transport recombinant proteins or protein domains to the cell surface of Gram-negative bacteria amongst others for antigen display. Genetic fusion of such antigens into autotransporters has yielded chimeras that can be used for vaccination pur...
Autores principales: | Phan, Trang H., Kuijl, Coen, Huynh, Dung T., Jong, Wouter S. P., Luirink, Joen, van Ulsen, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419823/ https://www.ncbi.nlm.nih.gov/pubmed/34488755 http://dx.doi.org/10.1186/s12934-021-01668-2 |
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