Changes in Nuclear Gene Expression Related to Mitochondrial Function Affect Extracellular Matrix, Collagens, and Focal Adhesion in Keratoconus

PURPOSE: Mitochondrial DNA (mtDNA) abnormalities were previously found to be causative in the pathogenesis of various diseases. Here, comprehensive mitochondrial and nuclear sequence and transcript analyses, along with analyses of the methylation aspects of nuclear genes related to mitochondrial fun...

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Detalles Bibliográficos
Autores principales: Nowak-Malczewska, Dorota M., Karolak, Justyna A., Swierkowska, Joanna, Jaworska, Marcelina M., Kulinska, Karolina I., Polakowski, Piotr, Rydzanicz, Malgorzata, Ploski, Rafal, Szaflik, Jacek P., Gajecka, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419871/
https://www.ncbi.nlm.nih.gov/pubmed/34478492
http://dx.doi.org/10.1167/tvst.10.11.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419871/
https://www.ncbi.nlm.nih.gov/pubmed/34478492
http://dx.doi.org/10.1167/tvst.10.11.6

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