Downregulated CLIP3 induces radioresistance by enhancing stemness and glycolytic flux in glioblastoma

BACKGROUND: Glioblastoma Multiforme (GBM) is a malignant primary brain tumor in which the standard treatment, ionizing radiation (IR), achieves a median survival of about 15 months. GBM harbors glioblastoma stem-like cells (GSCs), which play a crucial role in therapeutic resistance and recurrence. M...

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Detalles Bibliográficos
Autores principales: Kang, Hyunkoo, Lee, Sungmin, Kim, Kyeongmin, Jeon, Jaewan, Kang, Seok-Gu, Youn, HyeSook, Kim, Hae Yu, Youn, BuHyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420000/
https://www.ncbi.nlm.nih.gov/pubmed/34488821
http://dx.doi.org/10.1186/s13046-021-02077-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420000/
https://www.ncbi.nlm.nih.gov/pubmed/34488821
http://dx.doi.org/10.1186/s13046-021-02077-4

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