Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux

BACKGROUND: Demethylzeylasteral (T-96) is a pharmacologically active triterpenoid monomer extracted from Tripterygium wilfordii Hook F (TWHF) that has been reported to exhibit anti-neoplastic effects against several types of cancer cells. However, the potential anti-tumour effects of T-96 against hu...

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Detalles Bibliográficos
Autores principales: Yang, Dong-lin, Zhang, Ya-jun, He, Liu-jun, Hu, Chun-sheng, Gao, Li-xia, Huang, Jiu-hong, Tang, Yan, Luo, Jie, Tang, Dian-yong, Chen, Zhong-zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420005/
https://www.ncbi.nlm.nih.gov/pubmed/34488902
http://dx.doi.org/10.1186/s40659-021-00350-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420005/
https://www.ncbi.nlm.nih.gov/pubmed/34488902
http://dx.doi.org/10.1186/s40659-021-00350-6

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