Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release

Although 15–20% of COVID‐19 patients experience hyper‐inflammation induced by massive cytokine production, cellular triggers of this process and strategies to target them remain poorly understood. Here, we show that the N‐terminal domain (NTD) of the SARS‐CoV‐2 spike protein substantially induces mu...

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Detalles Bibliográficos
Autores principales: Chan, Marina, Vijay, Siddharth, McNevin, John, McElrath, M Juliana, Holland, Eric C, Gujral, Taranjit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420181/
https://www.ncbi.nlm.nih.gov/pubmed/34486798
http://dx.doi.org/10.15252/msb.202110426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420181/
https://www.ncbi.nlm.nih.gov/pubmed/34486798
http://dx.doi.org/10.15252/msb.202110426

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