Subcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Cancer versus Noncancer Patients: An Analysis of Efficacy and Safety Variables from Two Studies

PURPOSE: Methylnaltrexone inhibits opioid-induced constipation (OIC) by binding to peripheral µ-opioid receptors without impacting central opioid receptor mediated analgesia. This analysis compared methylnaltrexone efficacy and safety among advanced illness patients with and without active cancer an...

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Detalles Bibliográficos
Autores principales: Chamberlain, Bruce H, Rhiner, Michelle, Slatkin, Neal E, Stambler, Nancy, Israel, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420564/
https://www.ncbi.nlm.nih.gov/pubmed/34512008
http://dx.doi.org/10.2147/JPR.S312731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420564/
https://www.ncbi.nlm.nih.gov/pubmed/34512008
http://dx.doi.org/10.2147/JPR.S312731

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