SARS-CoV-2 B.1.617 Mutations L452R and E484Q Are Not Synergistic for Antibody Evasion

The SARS-CoV-2 B.1.617 variant emerged in the Indian state of Maharashtra in late 2020. There have been fears that 2 key mutations seen in the receptor-binding domain, L452R and E484Q, would have additive effects on evasion of neutralizing antibodies. We report that spike bearing L452R and E484Q con...

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Detalles Bibliográficos
Autores principales: Ferreira, Isabella A T M, Kemp, Steven A, Datir, Rawlings, Saito, Akatsuki, Meng, Bo, Rakshit, Partha, Takaori-Kondo, Akifumi, Kosugi, Yusuke, Uriu, Keiya, Kimura, Izumi, Shirakawa, Kotaro, Abdullahi, Adam, Agarwal, Anurag, Ozono, Seiya, Tokunaga, Kenzo, Sato, Kei, Gupta, Ravindra K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420622/
https://www.ncbi.nlm.nih.gov/pubmed/34260717
http://dx.doi.org/10.1093/infdis/jiab368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420622/
https://www.ncbi.nlm.nih.gov/pubmed/34260717
http://dx.doi.org/10.1093/infdis/jiab368

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