Extracellular HSP90α Interacts With ER Stress to Promote Fibroblasts Activation Through PI3K/AKT Pathway in Pulmonary Fibrosis

Pulmonary fibrosis is characterized by alveolar epithelial cell injury, lung fibroblast proliferation, differentiation, and extracellular matrix (ECM) deposition. Our previous study indicated that extracellular HSP90α (eHSP90α) promotes pulmonary fibrosis by activating the MAPK signaling pathway. Th...

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Detalles Bibliográficos
Autores principales: Zhang, Jinming, Zhong, Wenshan, Liu, Yuanyuan, Chen, Weimou, Lu, Ye, Zeng, Zhaojin, Qiao, Yujie, Huang, Haohua, Wan, Xuan, Li, Wei, Meng, Xiaojing, Zou, Fei, Cai, Shaoxi, Dong, Hangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420756/
https://www.ncbi.nlm.nih.gov/pubmed/34497513
http://dx.doi.org/10.3389/fphar.2021.708462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420756/
https://www.ncbi.nlm.nih.gov/pubmed/34497513
http://dx.doi.org/10.3389/fphar.2021.708462

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