Therapeutic Targeting PLK1 by ON-01910.Na Is Effective in Local Treatment of Retinoblastoma

Cell cycle deregulation is involved in the pathogenesis of many cancers and is often associated with protein kinase aberrations, including the polo-like kinase 1 (PLK1). We used retinoblastoma, an intraocular malignancy that lacks targeted therapy, as a disease model and set out to reveal targetabil...

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Detalles Bibliográficos
Autores principales: Ma, Huan, Nie, Cong, Chen, Ying, Li, Jinmiao, Xie, Yanjie, Tang, Zhixin, Gao, Yang, Ai, Siming, Mao, Yuxiang, Sun, Qian, Lu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420894/
https://www.ncbi.nlm.nih.gov/pubmed/33573708
http://dx.doi.org/10.3727/096504021X16130322409507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420894/
https://www.ncbi.nlm.nih.gov/pubmed/33573708
http://dx.doi.org/10.3727/096504021X16130322409507

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