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Cost-Effectiveness and Cost–Utility Analysis of the Use of Clopidogrel and Pantoprazole in Comparison with Clopidogrel and Omeprazole for the Secondary Prevention of Myocardial Infarction in Iran

OBJECTIVE: Gastrointestinal bleeding, a side effect of clopidogrel, is usually prevented by proton-pump inhibitors (PPIs). Due to omeprazole's inhibitory effects on the liver enzyme CYP2C19, its concomitant use with clopidogrel is argued to increase the risk of myocardial infarction (MI) recurr...

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Detalles Bibliográficos
Autores principales: Amirsadri, Mohammadreza, Hajhashemi, Valiollah, Asemi, Amir Shahriar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420933/
https://www.ncbi.nlm.nih.gov/pubmed/34527614
http://dx.doi.org/10.4103/jrpp.JRPP_21_22