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TFEB phosphorylation on Serine 211 is induced by autophagy in human synovial fibroblasts and by p62/SQSTM1 overexpression in HEK293 cells

Autophagy receptor p62/SQSTM1 signals a complex network that links autophagy-lysosomal system to proteasome. Phosphorylation of p62 on Serine 349 (P-Ser349 p62) is involved in a cell protective, antioxidant pathway. We have shown previously that P-Ser349 p62 occurs and is rapidly degraded during hum...

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Detalles Bibliográficos
Autores principales: Relic, Biserka, Deroyer, Celine, Malaise, Olivier, Plener, Zelda, Gillet, Philippe, de Seny, Dominique, Malaise, Michel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421036/
https://www.ncbi.nlm.nih.gov/pubmed/34405859
http://dx.doi.org/10.1042/BCJ20210174