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Emerging roles of adhesion G protein-coupled receptors

Adhesion G protein-coupled receptors (aGPCRs) form a sub-group within the GPCR superfamily. Their distinctive structure contains an abnormally large N-terminal, extracellular region with a GPCR autoproteolysis-inducing (GAIN) domain. In most aGPCRs, the GAIN domain constitutively cleaves the recepto...

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Detalles Bibliográficos
Autores principales: Rosa, Matthew, Noel, Timothy, Harris, Matthew, Ladds, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421042/
https://www.ncbi.nlm.nih.gov/pubmed/34282836
http://dx.doi.org/10.1042/BST20201144