Impact of Epigenomic Hypermethylation at TP53 on Allogeneic Hematopoietic Cell Transplantation Outcomes for Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic stem cell disorders for which allogeneic hematopoietic cell transplantation (HCT) is currently the sole curative treatment. Epigenetic lesions are considered a major pathogenetic determinant in many cancers, and in MDS, epige...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Auer, Paul, Zhang, Tao, Spellman, Stephen, Carlson, Karen-Sue, Nazha, Aziz, Bolon, Yung-Tsi, Saber, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421055/
https://www.ncbi.nlm.nih.gov/pubmed/33992829
http://dx.doi.org/10.1016/j.jtct.2021.04.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421055/
https://www.ncbi.nlm.nih.gov/pubmed/33992829
http://dx.doi.org/10.1016/j.jtct.2021.04.027

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