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A novel cell-cycle-regulated interaction of the Bloom syndrome helicase BLM with Mcm6 controls replication-linked processes

The Bloom syndrome DNA helicase BLM contributes to chromosome stability through its roles in double-strand break repair by homologous recombination and DNA replication fork restart during the replication stress response. Loss of BLM activity leads to Bloom syndrome, which is characterized by extraor...

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Detalles Bibliográficos
Autores principales: Shastri, Vivek M, Subramanian, Veena, Schmidt, Kristina H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421143/
https://www.ncbi.nlm.nih.gov/pubmed/34370039
http://dx.doi.org/10.1093/nar/gkab663