Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14

Histone recognition constitutes a key epigenetic mechanism in gene regulation and cell fate decision. PHF14 is a conserved multi-PHD finger protein that has been implicated in organ development, tissue homeostasis, and tumorigenesis. Here we show that PHF14 reads unmodified histone H3((1–34)) throug...

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Detalles Bibliográficos
Autores principales: Zheng, Shuangping, Bi, Yucong, Chen, Haining, Gong, Bo, Jia, Shunji, Li, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421203/
https://www.ncbi.nlm.nih.gov/pubmed/34365506
http://dx.doi.org/10.1093/nar/gkab670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421203/
https://www.ncbi.nlm.nih.gov/pubmed/34365506
http://dx.doi.org/10.1093/nar/gkab670

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