Cargando…

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Gene deletion and gene expression alteration can lead to growth defects that are amplified or reduced when a second mutation is present in the same cells. We performed 154 genetic interaction mapping (GIM) screens with query mutants related with RNA metabolism and estimated the growth rates of about...

Descripción completa

Detalles Bibliográficos
Autores principales: Decourty, Laurence, Malabat, Christophe, Frachon, Emmanuel, Jacquier, Alain, Saveanu, Cosmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421204/
https://www.ncbi.nlm.nih.gov/pubmed/34358317
http://dx.doi.org/10.1093/nar/gkab680