Dissecting and tuning primer editing by proofreading polymerases

Proofreading polymerases have 3′ to 5′ exonuclease activity that allows the excision and correction of mis-incorporated bases during DNA replication. In a previous study, we demonstrated that in addition to correcting substitution errors and lowering the error rate of DNA amplification, proofreading...

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Detalles Bibliográficos
Autores principales: Gohl, Daryl M, Auch, Benjamin, Certano, Amanda, LeFrançois, Brice, Bouevitch, Anne, Doukhanine, Evgueni, Fragel, Christina, Macklaim, Jean, Hollister, Emily, Garbe, John, Beckman, Kenneth B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421222/
https://www.ncbi.nlm.nih.gov/pubmed/34125893
http://dx.doi.org/10.1093/nar/gkab471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421222/
https://www.ncbi.nlm.nih.gov/pubmed/34125893
http://dx.doi.org/10.1093/nar/gkab471

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