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Dissecting and tuning primer editing by proofreading polymerases
Proofreading polymerases have 3′ to 5′ exonuclease activity that allows the excision and correction of mis-incorporated bases during DNA replication. In a previous study, we demonstrated that in addition to correcting substitution errors and lowering the error rate of DNA amplification, proofreading...
Autores principales: | Gohl, Daryl M, Auch, Benjamin, Certano, Amanda, LeFrançois, Brice, Bouevitch, Anne, Doukhanine, Evgueni, Fragel, Christina, Macklaim, Jean, Hollister, Emily, Garbe, John, Beckman, Kenneth B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421222/ https://www.ncbi.nlm.nih.gov/pubmed/34125893 http://dx.doi.org/10.1093/nar/gkab471 |
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