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Co-transcriptional RNA cleavage by Drosha homolog Pac1 triggers transcription termination in fission yeast

Transcription termination of protein-coding genes in eukaryotic cells usually relies on a tight coordination between the cleavage and polyadenylation of the pre-mRNA, and 5′-3′ degradation of the downstream nascent transcript. Here we investigated the contribution of the essential fission yeast endo...

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Detalles Bibliográficos
Autores principales: Yague-Sanz, Carlo, Duval, Maxime, Larochelle, Marc, Bachand, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421224/
https://www.ncbi.nlm.nih.gov/pubmed/34352089
http://dx.doi.org/10.1093/nar/gkab654