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Structural basis for glucocorticoid receptor recognition of both unmodified and methylated binding sites, precursors of a modern recognition element
The most common form of DNA methylation involves the addition of a methyl group to a cytosine base in the context of a cytosine–phosphate–guanine (CpG) dinucleotide. Genomes from more primitive organisms are more abundant in CpG sites that, through the process of methylation, deamination and subsequ...
Autores principales: | Liu, Xu, Weikum, Emily R, Tilo, Desiree, Vinson, Charles, Ortlund, Eric A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421226/ https://www.ncbi.nlm.nih.gov/pubmed/34289059 http://dx.doi.org/10.1093/nar/gkab605 |
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