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Treatment potential of LPCN 1144 on liver health and metabolic regulation in a non-genomic, high fat diet induced NASH rabbit model

PURPOSE: Low free testosterone (T) level in men is independently associated with presence and severity of Non-Alcoholic Steatohepatitis (NASH). The histological and molecular effects of oral testosterone prodrug LPCN 1144 treatment on hepatic fibrosis and NASH features are unknown. A metabolic syndr...

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Detalles Bibliográficos
Autores principales: Comeglio, P., Sarchielli, E., Filippi, S., Cellai, I., Guarnieri, G., Morelli, A., Rastrelli, G., Maseroli, E., Cipriani, S., Mello, T., Galli, A., Bruno, B. J., Kim, K., Vangara, K., Papangkorn, K., Chidambaram, N., Patel, M. V., Maggi, M., Vignozzi, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421272/
https://www.ncbi.nlm.nih.gov/pubmed/33586025
http://dx.doi.org/10.1007/s40618-021-01522-7