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The regulatory light chain mediates inactivation of myosin motors during active shortening of cardiac muscle

The normal function of heart muscle depends on its ability to contract more strongly at longer length. Increased venous filling stretches relaxed heart muscle cells, triggering a stronger contraction in the next beat- the Frank-Starling relation. Conversely, heart muscle cells are inactivated when t...

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Detalles Bibliográficos
Autores principales: Kampourakis, Thomas, Irving, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421338/
https://www.ncbi.nlm.nih.gov/pubmed/34489440
http://dx.doi.org/10.1038/s41467-021-25601-8