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The regulatory light chain mediates inactivation of myosin motors during active shortening of cardiac muscle
The normal function of heart muscle depends on its ability to contract more strongly at longer length. Increased venous filling stretches relaxed heart muscle cells, triggering a stronger contraction in the next beat- the Frank-Starling relation. Conversely, heart muscle cells are inactivated when t...
Autores principales: | Kampourakis, Thomas, Irving, Malcolm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421338/ https://www.ncbi.nlm.nih.gov/pubmed/34489440 http://dx.doi.org/10.1038/s41467-021-25601-8 |
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