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Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing

Developmental steps in the trypanosome life-cycle involve transition between replicative and non-replicative forms specialised for survival in, and transmission between, mammalian and tsetse fly hosts. Here, using oligopeptide-induced differentiation in vitro, we model the progressive development of...

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Detalles Bibliográficos
Autores principales: Briggs, Emma M., Rojas, Federico, McCulloch, Richard, Matthews, Keith R., Otto, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421343/
https://www.ncbi.nlm.nih.gov/pubmed/34489460
http://dx.doi.org/10.1038/s41467-021-25607-2