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Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing
Developmental steps in the trypanosome life-cycle involve transition between replicative and non-replicative forms specialised for survival in, and transmission between, mammalian and tsetse fly hosts. Here, using oligopeptide-induced differentiation in vitro, we model the progressive development of...
Autores principales: | Briggs, Emma M., Rojas, Federico, McCulloch, Richard, Matthews, Keith R., Otto, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421343/ https://www.ncbi.nlm.nih.gov/pubmed/34489460 http://dx.doi.org/10.1038/s41467-021-25607-2 |
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