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Spectroscopic glimpses of the transition state of ATP hydrolysis trapped in a bacterial DnaB helicase

The ATP hydrolysis transition state of motor proteins is a weakly populated protein state that can be stabilized and investigated by replacing ATP with chemical mimics. We present atomic-level structural and dynamic insights on a state created by ADP aluminum fluoride binding to the bacterial DnaB h...

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Detalles Bibliográficos
Autores principales: Malär, Alexander A., Wili, Nino, Völker, Laura A., Kozlova, Maria I., Cadalbert, Riccardo, Däpp, Alexander, Weber, Marco E., Zehnder, Johannes, Jeschke, Gunnar, Eckert, Hellmut, Böckmann, Anja, Klose, Daniel, Mulkidjanian, Armen Y., Meier, Beat H., Wiegand, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421360/
https://www.ncbi.nlm.nih.gov/pubmed/34489448
http://dx.doi.org/10.1038/s41467-021-25599-z