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Spectroscopic glimpses of the transition state of ATP hydrolysis trapped in a bacterial DnaB helicase
The ATP hydrolysis transition state of motor proteins is a weakly populated protein state that can be stabilized and investigated by replacing ATP with chemical mimics. We present atomic-level structural and dynamic insights on a state created by ADP aluminum fluoride binding to the bacterial DnaB h...
Autores principales: | Malär, Alexander A., Wili, Nino, Völker, Laura A., Kozlova, Maria I., Cadalbert, Riccardo, Däpp, Alexander, Weber, Marco E., Zehnder, Johannes, Jeschke, Gunnar, Eckert, Hellmut, Böckmann, Anja, Klose, Daniel, Mulkidjanian, Armen Y., Meier, Beat H., Wiegand, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421360/ https://www.ncbi.nlm.nih.gov/pubmed/34489448 http://dx.doi.org/10.1038/s41467-021-25599-z |
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