Gelatin methacrylate hydrogels culture model for glioblastoma cells enriches for mesenchymal-like state and models interactions with immune cells

Glioblastoma is the most lethal primary malignant brain tumor in adults. Simplified two-dimensional (2D) cell culture and neurospheres in vitro models fail to recapitulate the complexity of the tumor microenvironment, limiting its ability to predict therapeutic response. Three-dimensional (3D) scaff...

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Detalles Bibliográficos
Autores principales: Shah, Nameeta, Hallur, Pavan M., Ganesh, Raksha A., Sonpatki, Pranali, Naik, Divya, Chandrachari, Komal Prasad, Puchalski, Ralph B., Chaubey, Aditya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421368/
https://www.ncbi.nlm.nih.gov/pubmed/34489494
http://dx.doi.org/10.1038/s41598-021-97059-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421368/
https://www.ncbi.nlm.nih.gov/pubmed/34489494
http://dx.doi.org/10.1038/s41598-021-97059-z

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