Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naïve human B cells

A successful HIV vaccine eliciting broadly neutralizing antibodies (bnAbs) must overcome the hurdle of being able to activate naive precursor B cells encoding features within their germline B cell receptors (BCR) that allow recognition of broadly neutralizing epitopes. Knowledge of whether bnAb prec...

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Detalles Bibliográficos
Autores principales: Lee, Jeong Hyun, Toy, Laura, Kos, Justin T., Safonova, Yana, Schief, William R., Havenar-Daughton, Colin, Watson, Corey T., Crotty, Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421370/
https://www.ncbi.nlm.nih.gov/pubmed/34489473
http://dx.doi.org/10.1038/s41541-021-00376-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421370/
https://www.ncbi.nlm.nih.gov/pubmed/34489473
http://dx.doi.org/10.1038/s41541-021-00376-7

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