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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance

Following injury, cells in regenerative tissues have the ability to regrow. The mechanisms whereby regenerating cells adapt to injury-induced stress conditions and activate the regenerative program remain to be defined. Here, using the mammalian neonatal heart regeneration model, we show that Nrf1,...

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Detalles Bibliográficos
Autores principales: Cui, Miao, Atmanli, Ayhan, Morales, Maria Gabriela, Tan, Wei, Chen, Kenian, Xiao, Xue, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421386/
https://www.ncbi.nlm.nih.gov/pubmed/34489413
http://dx.doi.org/10.1038/s41467-021-25653-w