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Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance
Following injury, cells in regenerative tissues have the ability to regrow. The mechanisms whereby regenerating cells adapt to injury-induced stress conditions and activate the regenerative program remain to be defined. Here, using the mammalian neonatal heart regeneration model, we show that Nrf1,...
Autores principales: | Cui, Miao, Atmanli, Ayhan, Morales, Maria Gabriela, Tan, Wei, Chen, Kenian, Xiao, Xue, Xu, Lin, Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421386/ https://www.ncbi.nlm.nih.gov/pubmed/34489413 http://dx.doi.org/10.1038/s41467-021-25653-w |
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