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Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Cell death is a critical process that occurs normally in health and disease. However, its study is limited due to available technologies that only detect very late stages in the process or specific death mechanisms. Here, we report the development of a family of fluorescent biosensors called genetic...

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Detalles Bibliográficos
Autores principales: Linsley, Jeremy W., Shah, Kevan, Castello, Nicholas, Chan, Michelle, Haddad, Dominik, Doric, Zak, Wang, Shijie, Leks, Wiktoria, Mancini, Jay, Oza, Viral, Javaherian, Ashkan, Nakamura, Ken, Kokel, David, Finkbeiner, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421388/
https://www.ncbi.nlm.nih.gov/pubmed/34489414
http://dx.doi.org/10.1038/s41467-021-25549-9