Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin

The vascular endothelium is present within metabolic organs and actively regulates energy metabolism. Here we show osteocalcin, recognized as a bone-secreted metabolic hormone, is expressed in mouse primary endothelial cells isolated from heart, lung and liver. In human osteocalcin promoter-driven g...

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Detalles Bibliográficos
Autores principales: Mao, Hua, Li, Luge, Fan, Qiying, Angelini, Aude, Saha, Pradip K., Coarfa, Cristian, Rajapakshe, Kimal, Perera, Dimuthu, Cheng, Jizhong, Wu, Huaizhu, Ballantyne, Christie M., Sun, Zheng, Xie, Liang, Pi, Xinchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421392/
https://www.ncbi.nlm.nih.gov/pubmed/34489478
http://dx.doi.org/10.1038/s41467-021-25673-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421392/
https://www.ncbi.nlm.nih.gov/pubmed/34489478
http://dx.doi.org/10.1038/s41467-021-25673-6

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