Cargando…
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin
The vascular endothelium is present within metabolic organs and actively regulates energy metabolism. Here we show osteocalcin, recognized as a bone-secreted metabolic hormone, is expressed in mouse primary endothelial cells isolated from heart, lung and liver. In human osteocalcin promoter-driven g...
| Autores principales: | , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421392/ https://www.ncbi.nlm.nih.gov/pubmed/34489478 http://dx.doi.org/10.1038/s41467-021-25673-6 |