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Mitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases
Macroautophagic recycling of dysfunctional mitochondria, known as mitophagy, is essential for mitochondrial homeostasis and cell viability. Accumulation of defective mitochondria and impaired mitophagy have been widely implicated in many neurodegenerative diseases, and loss-of-function mutations of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421394/ https://www.ncbi.nlm.nih.gov/pubmed/34489512 http://dx.doi.org/10.1038/s41598-021-97148-z |