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Ca(2+) channel blockade reduces cocaine’s vasoconstriction and neurotoxicity in the prefrontal cortex
Cocaine profoundly affects both cerebral blood vessels and neuronal activity in the brain. The vasoconstrictive effects of cocaine, concurrently with its effects on neuronal [Ca(2+)](i) accumulation are likely to jeopardize neuronal tissue that in the prefrontal cortex (PFC) could contribute to impa...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421405/ https://www.ncbi.nlm.nih.gov/pubmed/34489397 http://dx.doi.org/10.1038/s41398-021-01573-7 |