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Ca(2+) channel blockade reduces cocaine’s vasoconstriction and neurotoxicity in the prefrontal cortex

Cocaine profoundly affects both cerebral blood vessels and neuronal activity in the brain. The vasoconstrictive effects of cocaine, concurrently with its effects on neuronal [Ca(2+)](i) accumulation are likely to jeopardize neuronal tissue that in the prefrontal cortex (PFC) could contribute to impa...

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Detalles Bibliográficos
Autores principales:	Du, Congwu, Park, Kicheon, Allen, Craig P., Hu, Xiu-Ti, Volkow, Nora D., Pan, Yingtain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421405/ https://www.ncbi.nlm.nih.gov/pubmed/34489397 http://dx.doi.org/10.1038/s41398-021-01573-7

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