Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

Pdr5, a member of the extensive ABC transporter superfamily, is representative of a clinically relevant subgroup involved in pleiotropic drug resistance. Pdr5 and its homologues drive drug efflux through uncoupled hydrolysis of nucleotides, enabling organisms such as baker’s yeast and pathogenic fun...

Descripción completa

Detalles Bibliográficos
Autores principales: Harris, Andrzej, Wagner, Manuel, Du, Dijun, Raschka, Stefanie, Nentwig, Lea-Marie, Gohlke, Holger, Smits, Sander H. J., Luisi, Ben F., Schmitt, Lutz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421411/
https://www.ncbi.nlm.nih.gov/pubmed/34489436
http://dx.doi.org/10.1038/s41467-021-25574-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421411/
https://www.ncbi.nlm.nih.gov/pubmed/34489436
http://dx.doi.org/10.1038/s41467-021-25574-8

Ejemplares similares