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Cardiomyocyte-specific deletion of β-catenin protects mouse hearts from ventricular arrhythmias after myocardial infarction

Wnt/β-catenin signaling is activated in the heart after myocardial infarction (MI). This study aims to investigate if β-catenin deletion affects post-MI ion channel gene alterations and ventricular tachycardias (VT). MI was induced by permanent ligation of left anterior descending artery in wild-typ...

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Detalles Bibliográficos
Autores principales: Wang, Jerry, Xia, Ying, Lu, Aizhu, Wang, Hongwei, Davis, Darryl R., Liu, Peter, Beanlands, Rob S., Liang, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421412/
https://www.ncbi.nlm.nih.gov/pubmed/34489488
http://dx.doi.org/10.1038/s41598-021-97176-9