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Directed evolution of prenylated FMN-dependent Fdc supports efficient in vivo isobutene production

Isobutene is a high value gaseous alkene used as fuel additive and a chemical building block. As an alternative to fossil fuel derived isobutene, we here develop a modified mevalonate pathway for the production of isobutene from glucose in vivo. The final step in the pathway consists of the decarbox...

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Detalles Bibliográficos
Autores principales: Saaret, Annica, Villiers, Benoît, Stricher, François, Anissimova, Macha, Cadillon, Mélodie, Spiess, Reynard, Hay, Sam, Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421414/
https://www.ncbi.nlm.nih.gov/pubmed/34489427
http://dx.doi.org/10.1038/s41467-021-25598-0